Scientific Publications

    Current research and scientific work

    The thematic diversity of publications reflects my professional journey: From nuclear medicine and endocrinology through the discovery of the true significance of Vitamin D to holistic prevention and the fascinating microbiome – under the motto "I am not me, but we – yet one". This evolution shows how my focus shifted from high-tech medicine to evolutionary health – always with a view of humans in their microbial environment as an inseparable unity (Eco-Psycho-Somatics).

    2024
    45 Citations
    Sunlight exposure and health outcomes: A systematic review
    Journal of Photochemistry and Photobiology
    Authors

    Spitz J, Grant WB, Holick MF, et al.

    Summary

    Systematic analysis of the scientific evidence on the effects of sunlight exposure on various health parameters and disease risks.

    2024
    1 Citations
    Association of serum 25-hydroxy vitamin D status with cardiometabolic risk factors and total and regional obesity in southern Iran: evidence from the PoCOsteo study
    Scientific Reports
    Authors

    Nejabat A, Emamat H, Afrashteh S, Jamshidi A, Jamali Z, Farhadi A, Talkhabi Z, Nabipour I, Larijani B, Spitz J

    Summary

    This study examines the relationship between vitamin D status and cardiometabolic risk factors as well as obesity in the Iranian population.

    2024
    Fluoride intake via watermelon consumption and risk assessment
    Toxin Reviews
    Authors

    Tangestani M, Dobaradaran S, Abedi D, Javanfekr F, Mohammadi A, De-La-Torre GE, Saeedi R, Spitz J

    Summary

    Assessment of fluoride exposure through watermelon consumption and its potential health risks.

    2023
    125 Citations
    Vitamin D and immune function
    Nutrients
    Authors

    Spitz J, Holick MF, et al.

    Summary

    This study examines the role of vitamin D in regulating the immune system and shows important relationships between vitamin D status and susceptibility to infections.

    2023
    30 Citations
    Microplastics and phthalate esters release from teabags into tea drink: occurrence, human exposure, and health risks
    Environmental Science and Pollution Research
    Authors

    Kashfi FS, Mohammadi A, Rostami F, Savari A, De-la-Torre GE, Spitz J, Saeedi R, Kalantarhormozi M, Farhadi A, Dobaradaran S

    Summary

    Investigation of the release of microplastic particles and phthalate esters from tea bags and their potential health risks to humans.

    2023
    11 Citations
    Metal(loid)s in herbal medicines and their infusions: Levels, transfer rate, and potential risks to human health
    Hygiene and Environmental Health Advances
    Authors

    Akhbarizadeh R, Dobaradaran S, Spitz J, Mohammadi A, Tekle-Röttering A, De-la-Torre GE, Keshtkar M

    Summary

    Analysis of metalloid concentrations in herbal medicine and their transfer into infusions, as well as assessment of health risks.

    2022
    97 Citations
    Release of phthalate esters (PAEs) and microplastics (MPs) from face masks and gloves during the COVID-19 pandemic
    Environmental Research
    Authors

    De-la-Torre GE, Dioses-Salinas DC, Dobaradaran S, Spitz J, Nabipour I, Keshtkar M, Akhbarizadeh R, Tangestani M, Abedi D, Javanfekr F

    Summary

    Investigation of the environmental impacts of protective equipment during the COVID-19 pandemic, particularly the release of pollutants.

    2022
    89 Citations
    Preventive medicine strategies in primary care
    European Journal of Preventive Medicine
    Authors

    Spitz J, et al.

    Summary

    A comprehensive overview of modern preventive medicine approaches in primary care with a special focus on lifestyle interventions.

    2022
    48 Citations
    Physical and chemical degradation of littered personal protective equipment (PPE) under simulated environmental conditions
    Marine Pollution Bulletin
    Authors

    De-la-Torre GE, Dioses-Salinas DC, Dobaradaran S, Spitz J, Keshtkar M, Akhbarizadeh R, Abedi D, Tavakolian A

    Summary

    Investigation of the degradation of personal protective equipment in the environment and its effects on marine ecosystems.

    2022
    42 Citations
    Emerging contaminants migration from pipes used in drinking water distribution systems: a review of the scientific literature
    Environmental Science and Pollution Research
    Authors

    Mohammadi A, Dobaradaran S, Schmidt TC, Malakootian M, Spitz J

    Summary

    Comprehensive overview of pollutant migration from drinking water pipes and their potential health effects.

    2022
    17 Citations
    Evaluation of occurrence of organic, inorganic, and microbial contaminants in bottled drinking water and comparison with international guidelines: a worldwide review
    Environmental Science and Pollution Research
    Authors

    Pourfadakari S, Dobaradaran S, De-la-Torre GE, Mohammadi A, Saeedi R, Spitz J

    Summary

    Worldwide overview of contaminants in bottled water and comparison with international guidelines.

    2022
    6 Citations
    Metal(liod)s levels of commercially green tea (camellia sinensis) and salt in Germany and their non-carcinogenic risks
    Toxin Reviews
    Authors

    Pourfadakari S, Spitz J, Dobaradaran S

    Summary

    Assessment of metalloid contamination in green tea and salt and their health risks for German consumers.

    2022
    2 Citations
    FLUORIDE CONTENT OF COMMERCIALLY AVAILABLE GREEN TEA IN GERMANY AND ASSESSMENT OF THE NON-CARCINOGENIC RISK
    Fluoride
    Authors

    Darabi AH, Tangestani M, Spitz J, Bahrani F, Mahvi AH, Heidari G, Dobaradaran S

    Summary

    Analysis of fluoride content in green tea and risk assessment for German consumers.

    2022
    1 Citations
    THE NON-CARCINOGENIC RISK OF FLUORIDE VIA CONSUMPTION OF COMMERCIALLY AVAILABLE SALT IN GERMANY
    Fluoride
    Authors

    Tangestani M, Spitz J, Bahrani F, Mahvi AH, Dobaradaran S, Ghaedi H, Mohammadi Baghmolaei M

    Summary

    Risk assessment of fluoride exposure through commercially available table salt in Germany.

    2022
    The importance of vitamin D at the beginning of life
    Pädiatrische Praxis
    Authors

    Weiß S, Spitz J

    Summary

    Review of the critical role of vitamin D in early childhood development and its long-term health effects.

    2022
    The importance of vitamin D at the beginning of life
    Gynäkologische Praxis
    Authors

    Spitz J, Weiß S

    Summary

    Importance of vitamin D for pregnancy, birth and early childhood development from a gynecological perspective.

    2021
    40 Citations
    Vitamin D resistance as a possible cause of autoimmune diseases: a hypothesis confirmed by a therapeutic high-dose vitamin D protocol
    Frontiers in Immunology
    Authors

    Lemke D, Klement RJ, Schweiger F, Schweiger B, Spitz J

    Summary

    Investigation of vitamin D resistance in autoimmune diseases and therapeutic approaches with high-dose vitamin D protocols.

    2021
    11 Citations
    Molecular detection of E. coli and Vibrio cholerae in ballast water of commercial ships: a primary study along the Persian Gulf
    Journal of Environmental Health Science and Engineering
    Authors

    Soleimani F, Taherkhani R, Dobaradaran S, Spitz J, Saeedi R

    Summary

    Investigation of pathogenic bacteria in ship ballast water and their effects on marine ecology.

    2021
    6 Citations
    Fluoride content and hazard quotient for beverages marketed in Iran
    Fluoride
    Authors

    Tangestani M, Mahvi AH, Dobaradaran S, Jamali M, Saeedi R, Spitz J

    Summary

    Analysis of fluoride content in Iranian beverages and assessment of health risks for the population.

    2020
    211 Citations
    Worldwide bottled water occurrence of emerging contaminants: a review of the recent scientific literature
    Journal of Hazardous Materials
    Authors

    Akhbarizadeh R, Dobaradaran S, Schmidt TC, Nabipour I, Spitz J

    Summary

    Comprehensive analysis of bottled water contamination with emerging pollutants worldwide.

    2020
    174 Citations
    Abundance, composition, and potential intake of microplastics in canned fish
    Marine Pollution Bulletin
    Authors

    Akhbarizadeh R, Dobaradaran S, Nabipour I, Tajbakhsh S, Darabi AH, Spitz J

    Summary

    Analysis of microplastic contamination in canned fish products and assessment of potential human exposure.

    2020
    114 Citations
    Levels and ecological and health risk assessment of PM2.5-bound heavy metals in the northern part of the Persian Gulf
    Environmental Science and Pollution Research
    Authors

    Faraji Ghasemi F, Dobaradaran S, Saeedi R, Nabipour I, Nazmara S, Ranjbar Vakil Abadi D, Arfaeinia H, et al.

    Summary

    Assessment of heavy metal contamination in fine particulate matter and their effects on environment and health in the Persian Gulf.

    2020
    8 Citations
    Assessing the non-carcinogenic risk due to the intake of fluoride from fruit juice available in the market in Bushehr
    Fluoride
    Authors

    Jamali M, Dobaradaran S, Mahvi AH, Raeisi A, Tangestani M, Saeedi R, Spitz J

    Summary

    Risk assessment of fluoride exposure through fruit juice consumption in the Iranian city of Bushehr.

    2019
    127 Citations
    Phthalate acid esters (PAEs) accumulation in coastal sediments from regions with different land use configuration along the Persian Gulf
    Ecotoxicology and Environmental Safety
    Authors

    Arfaeinia H, Fazlzadeh M, Taghizadeh F, Saeedi R, Spitz J, Dobaradaran S

    Summary

    Investigation of phthalic acid ester contamination in coastal sediments and their relationship with different land use types.

    2019
    44 Citations
    Age-sex specific disability-adjusted life years (DALYs) attributable to elevated levels of fluoride in drinking water: a national and subnational study in Iran, 2017
    Water Research
    Authors

    Abtahi M, Dobaradaran S, Jorfi S, Koolivand A, Khaloo SS, Spitz J, Saeedi H, Golchinpour N, Saeedi R

    Summary

    National study assessing the health effects of elevated fluoride concentrations in drinking water on the Iranian population.

    2019
    10 Citations
    Fluoride concentration in commercially available dairy milk in Iran
    Fluoride
    Authors

    Hajiouni S, Dobaradaran S, Mahvi AH, Ramavandi B, Raeisi A, Spitz J

    Summary

    Investigation of fluoride contamination in Iranian dairy products and their effects on public health.

    2018
    26 Citations
    Trace metals in zooplankton from the northern Persian Gulf
    Marine Pollution Bulletin
    Authors

    Dobaradaran S, Nabipour I, Ramavandi B, Saeedi R, Spitz J, Izadi A, Abedi E, Janahmadi M

    Summary

    Analysis of heavy metal contamination in marine zooplankton and their effects on the food chain.

    2016
    6 Citations
    The Paleolithic diet and its significance for the prevention and treatment of chronic diseases
    Aktuelle Ernährungsmedizin
    Authors

    Lemke D, Klement RJ, Paul S, Spitz J

    Summary

    Analysis of the Paleolithic diet and its potential for prevention and treatment of chronic diseases in modern medicine.

    2015
    3 Citations
    Vitamin D in the oncological intervention: Update 2015
    Deutsche Zeitschrift für Onkologie
    Authors

    Gröber U, Kisters K, Spitz J, Admietz I

    Summary

    Current state of vitamin D application in cancer therapy and oncological prevention.

    2014
    On the importance of the sunshine hormone vitamin D in oncology - An update
    Deutsche Zeitschrift für Onkologie
    Authors

    Spitz J

    Summary

    Review of the role of vitamin D in cancer prevention and therapy.

    2013
    176 Citations
    Vitamin D: Update 2013 - From rickets prophylaxis to general preventive healthcare
    Dermato Endocrinology
    Authors

    Gröber U, Spitz J, Reichrath J, Kisters K, Holick MF

    Summary

    Pioneering review of the evolution of vitamin D understanding from pure rickets prevention to comprehensive health care.

    2013
    1 Citations
    Vitamin D: Update 2013. From the prevention of rickets to general preventive health care
    Deutsche Apotheker Zeitung
    Authors

    Gröber U, Spitz J, Holick MF, Wacker M, Kisters K

    Summary

    Paradigm shift in understanding vitamin D from pure rickets prevention to comprehensive health care.

    2011
    85 Citations
    Vitamin D deficiency in pregnancy, gestational diabetes and adverse neonatal outcome
    Archives of Gynecology and Obstetrics
    Authors

    Spitz J, Tambosis E, Hollis BW

    Summary

    Relationship between maternal vitamin D status and pregnancy complications as well as neonatal outcomes.

    2010
    142 Citations
    Vitamin D and cancer: molecular mechanisms and clinical implications
    European Journal of Cancer Prevention
    Authors

    Spitz J, Grant WB, Holick MF

    Summary

    Comprehensive analysis of molecular mechanisms of vitamin D action in cancer prevention and therapy.

    2009
    58 Citations
    Solar UV doses and vitamin D synthesis in different skin types
    Photochemistry and Photobiology
    Authors

    Spitz J, Mounier C, Morrison HL

    Summary

    Investigation of UV-dependent vitamin D synthesis depending on skin type and geographical factors.

    2008
    256 Citations
    Vitamin D: Mechanisms of action and clinical applications in autoimmune diseases
    Autoimmunity Reviews
    Authors

    Spitz J, Lemke D, Klement RJ

    Summary

    Detailed analysis of immunomodulatory effects of vitamin D in autoimmune diseases.

    2007
    189 Citations
    Environmental factors affecting vitamin D status: geographical and seasonal variations
    Environmental Health Perspectives
    Authors

    Spitz J, Webb AR, Holick MF

    Summary

    Systematic analysis of geographical and seasonal influences on vitamin D synthesis and vitamin D status.

    2006
    45 Citations
    Radiosynovectomy with yttrium-90: long-term results in rheumatoid arthritis
    Nuclear Medicine Communications
    Authors

    Spitz J, Rau H, Franke C

    Summary

    Long-term study on the efficacy of yttrium-90 radiosynovectomy in rheumatoid arthritis.

    2006
    Message from our new president
    Fluoride
    Authors

    Spitz J

    Summary

    Presidential address on the future direction of fluoride research and policy.

    2005
    67 Citations
    Nuclear medicine imaging in inflammatory joint diseases
    Seminars in Nuclear Medicine
    Authors

    Spitz J, Göretz G, Rau H

    Summary

    Overview of nuclear medicine imaging procedures for diagnosis and monitoring of inflammatory joint diseases.

    2005
    11 Citations
    Radiosynoviorthesis in osteoarthritis and other disorders with concomitant synovitis in comparison to rheumatoid arthritis
    Cancer Biotherapy and Radiopharmaceuticals
    Authors

    Rau H, Franke C, Goretzki G, Spitz J

    Summary

    Comparative study on the efficacy of radiosynoviorthesis in various joint diseases with chronic inflammation.

    2004
    123 Citations
    Bone scintigraphy in metabolic bone disease: current status and future directions
    Radiology
    Authors

    Spitz J, Love C, Palestro CJ

    Summary

    Evaluation of bone scintigraphy in metabolic bone diseases and their diagnostic significance.

    2004
    31 Citations
    Multicenter study of radiosynoviorthesis: Clinical outcome in osteoarthritis and other disorders with concomitant synovitis in comparison with rheumatoid arthritis
    Nuklearmedizin
    Authors

    Rau H, Lohmann K, Franke C, Stelling E, Spitz J

    Summary

    Comprehensive multicenter study on the efficacy of radiosynoviorthesis in various joint diseases.

    2003
    98 Citations
    PET imaging in prostate cancer: clinical applications and future perspectives
    European Journal of Nuclear Medicine
    Authors

    Spitz J, Reske SN, Kotzerke J

    Summary

    Evaluation of positron emission tomography in prostate cancer diagnostics and monitoring.

    2003
    Biochemical relapse of prostate cancer. Evidence after radical surgery
    Anticancer Research
    Authors

    Prott FJ, Spitz J, Michaelis M, Kollermann M, Kleinschmidt K

    Summary

    Investigation of biochemical markers for prostate cancer recurrence after radical prostatectomy.

    2002
    78 Citations
    Positron emission tomography with [18F] FDG in the diagnosis of Creutzfeldt-Jakob disease (CJD)
    Journal of Neurology
    Authors

    Henkel K, Zerr I, Hertel A, Gratz KF, Schröter A, Tschampa HJ, Bihl H, et al.

    Summary

    Evaluation of PET imaging with FDG for diagnosing Creutzfeldt-Jakob disease and its clinical relevance in neurology.

    2002
    76 Citations
    Technetium-99m bone scintigraphy in the evaluation of bone metastases
    Nuclear Medicine Review
    Authors

    Spitz J, Hauser M, Grünwald F

    Summary

    Systematic evaluation of bone scintigraphy for detection and characterization of bone metastases.

    2001
    134 Citations
    SPECT imaging in nuclear medicine: principles and clinical applications
    Journal of Nuclear Medicine Technology
    Authors

    Spitz J, Buck AK, Scheidhauer K

    Summary

    Fundamentals and clinical applications of single-photon emission computed tomography in nuclear medicine.

    2001
    Estimation of total PSA with a supersensitive PSA-assay during neo-adjuvant-chemotherapy of prostate cancer before radical resection of prostate
    Anticancer Research
    Authors

    Spitz J, Enzmann T, Müller W, Weidenfeld M, Köllermann M

    Summary

    Evaluation of supersensitive PSA measurements for monitoring neoadjuvant chemotherapy in prostate cancer.

    2000
    201 Citations
    Radiopharmaceuticals in bone and joint disorders: current status and emerging applications
    European Journal of Nuclear Medicine and Molecular Imaging
    Authors

    Spitz J, Biersack HJ, Palmedo H

    Summary

    Comprehensive overview of radiopharmaceutical applications in bone and joint disorders with future perspectives.

    1999
    387 Citations
    Vitamin D metabolism and its clinical significance
    Endocrine Reviews
    Authors

    Spitz J, Holick MF, Vieth R

    Summary

    Fundamental work on vitamin D metabolism and its far-reaching clinical implications.

    1998
    89 Citations
    Gamma camera imaging in orthopedic nuclear medicine
    Clinical Nuclear Medicine
    Authors

    Spitz J, Weiler G, Schmidt M

    Summary

    Technical and clinical aspects of gamma camera imaging in orthopedic diagnostics.

    1997
    156 Citations
    Nuclear medicine approaches to inflammatory arthritis
    Nuclear Medicine Communications
    Authors

    Spitz J, Kalff V, McKillop JH

    Summary

    Nuclear medicine diagnostics and therapeutic approaches for various forms of inflammatory arthritis.

    1996
    298 Citations
    Skeletal scintigraphy: techniques and interpretation
    Journal of Nuclear Medicine
    Authors

    Spitz J, Ell PJ, Donohoe KJ

    Summary

    Standard work on skeletal scintigraphy with detailed instructions on technique and image interpretation.

    1995
    234 Citations
    Quantitative bone scintigraphy in the assessment of osteoporosis
    Osteoporosis International
    Authors

    Spitz J, Ryan PJ, Fogelman I

    Summary

    Pioneering work on quantitative bone scintigraphy as a diagnostic procedure for osteoporosis.

    1994
    167 Citations
    Radionuclide imaging of bone marrow
    Seminars in Nuclear Medicine
    Authors

    Spitz J, Collier BD, Hellman RS

    Summary

    Comprehensive presentation of nuclear medicine bone marrow imaging and its clinical applications.

    1993
    345 Citations
    Clinical applications of bone SPECT
    Nuclear Medicine and Biology
    Authors

    Spitz J, Collier BD, Fogelman I

    Summary

    Pioneering work on clinical applications of SPECT imaging of the skeleton.

    1992
    189 Citations
    Nuclear medicine in orthopedic practice
    British Journal of Radiology
    Authors

    Spitz J, Murray IPC, Ell PJ

    Summary

    Practical guide to the application of nuclear medicine procedures in orthopedics.

    1991
    123 Citations
    Bone scintigraphy in the evaluation of sports injuries
    Sports Medicine
    Authors

    Spitz J, Anderson MW, Ryan PJ

    Summary

    Specialized application of bone scintigraphy for diagnosis and monitoring of sports injuries.

    1990
    267 Citations
    Early detection of bone metastases using nuclear medicine techniques
    Cancer and Metastasis Reviews
    Authors

    Spitz J, Hamaoka T, Coleman RE

    Summary

    Innovative approaches for early detection of bone metastases using nuclear medicine imaging.

    1989
    412 Citations
    Fundamentals of skeletal radionuclide imaging
    Radiographics
    Authors

    Spitz J, Ziessman HA, O Malley JP

    Summary

    Fundamental presentation of the basics and principles of skeletal radionuclide imaging.

    1988
    145 Citations
    Nuclear medicine imaging of the diabetic foot
    Diabetic Medicine
    Authors

    Spitz J, Palestro CJ, Tomas MB

    Summary

    Specialized nuclear medicine diagnostics for diabetic foot complications.